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What does "onset" refer to in a general context?

A moment of success

The beginning of something unpleasant

In a general context, "onset" typically refers to the beginning or start, particularly of something that is often considered undesirable or unpleasant. This term is frequently used in medical scenarios to describe the initial appearance or commencement of a disease or symptoms, thus conveying a sense of urgency or concern related to that beginning.

For instance, in discussions of illnesses, one might speak about the onset of flu symptoms to indicate the moment when the illness first starts to affect an individual. This usage emphasizes the idea that the onset often marks the transition into a state that could lead to further complications or discomfort. The other options may relate to different contexts but do not encapsulate the general and commonly understood implications of "onset" as effectively as identifying it with the beginning of something unpleasant.

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A point of no return

A period of calmness

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